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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-7-7
|
| pubmed:abstractText |
A 70,XXX,+18 karyotype was found by chorionic villus sampling, while the fetal fibroblast culture of the affected fetus revealed a 47,XX,+18 karyotype. From several possible mechanisms, we assume that a second gamete fusion occurred after the first cell division of the zygote. According to this interpretation, the mosaicism arose in very early pregnancy (at the two-cell stage). This discrepancy can therefore be explained by selection pressure, due to the differentiation processes in the embryonic tissues.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0197-3851
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
301-6
|
| pubmed:dateRevised |
2004-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:8506231-Adult,
pubmed-meshheading:8506231-Chorionic Villi Sampling,
pubmed-meshheading:8506231-Diploidy,
pubmed-meshheading:8506231-Female,
pubmed-meshheading:8506231-Humans,
pubmed-meshheading:8506231-Karyotyping,
pubmed-meshheading:8506231-Maternal Age,
pubmed-meshheading:8506231-Mosaicism,
pubmed-meshheading:8506231-Ploidies,
pubmed-meshheading:8506231-Pregnancy,
pubmed-meshheading:8506231-Pregnancy, High-Risk,
pubmed-meshheading:8506231-Prenatal Diagnosis
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Evidence of a second gamete fusion after the first cleavage of the zygote in a 47,XX,+18/70,XXX,+18 mosaic. A remarkable diploid-triploid discrepancy after CVS.
|
| pubmed:affiliation |
Department of Human Genetics, State University of Groningen, The Netherlands.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|