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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-7-6
|
| pubmed:abstractText |
Seventy patients with multiple sclerosis (according to Poser's criteria) were clinically assessed and examined with MRI, multimodal evoked potentials (VEP, AEP, SSEP) and CSF analysis (transformed lymphocytes, IgG-Index, oligoclonal banding). In relation to the clinical criteria of McAlpine 40 patients had possible, 16 patients probable and 14 patients definite MS. 81% of the patients (73% possible MS, 94% probable MS, 93% definite MS) had multiple white matter lesions detected by MRI, 79% (78% possible MS, 94% probable MS, 64% definite MS) had an abnormal CSF profile and 67% (60% possible MS, 75% probable MS, 79% definite MS) abnormal results in multimodal EP testing. Of the patients who experienced only one attack (n = 40) 78% had multiple lesions on MRI, 88% had abnormal CSF-findings and 60% had pathologic EPs. Patients with two or more attacks showed in 87% multiple lesions on MRI, in 77% abnormal EPs and in 70% abnormal CSF findings. The number of abnormal MRI and EPs increases with the duration of the disease. 13 patients with a normal MRI were discussed separately. MRI is the most sensitive method in detecting the spatial pattern of disseminated lesions. To monitor the dissemination over time a careful clinical follow-up is still mandatory.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0028-2804
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
64
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
226-32
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8506010-Adolescent,
pubmed-meshheading:8506010-Adult,
pubmed-meshheading:8506010-Arousal,
pubmed-meshheading:8506010-Attention,
pubmed-meshheading:8506010-Brain,
pubmed-meshheading:8506010-Brain Stem,
pubmed-meshheading:8506010-Diagnosis, Differential,
pubmed-meshheading:8506010-Electroencephalography,
pubmed-meshheading:8506010-Evoked Potentials,
pubmed-meshheading:8506010-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:8506010-Female,
pubmed-meshheading:8506010-Humans,
pubmed-meshheading:8506010-Immunoglobulin G,
pubmed-meshheading:8506010-Immunoglobulins,
pubmed-meshheading:8506010-Lymphocyte Activation,
pubmed-meshheading:8506010-Magnetic Resonance Imaging,
pubmed-meshheading:8506010-Male,
pubmed-meshheading:8506010-Middle Aged,
pubmed-meshheading:8506010-Multiple Sclerosis,
pubmed-meshheading:8506010-Neurologic Examination,
pubmed-meshheading:8506010-Oligoclonal Bands,
pubmed-meshheading:8506010-Reaction Time
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
[The diagnostic value of nuclear magnetic resonance tomography, multimodal evoked potentials and cerebrospinal fluid examination in multiple sclerosis].
|
| pubmed:affiliation |
Neurologische Abteilung, Landesnervenklinik Salzburg.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|