Linked Life Data

8500332

Source:http://linkedlifedata.com/resource/pubmed/id/8500332

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-6-28
pubmed:abstractText
Measurements of electrical potential difference across isolated rabbit corneal endothelium (transendothelial electrical potential difference, TEPD) were used to evaluate the effect of two commonly used commercially prepared intraocular irrigation balanced salt solutions, BSS and BSS+, together with our own standard bicarbonate-containing control solution (BS). The highest and most durable TEPD values were obtained by using BSS+; TEPD began at 550 microV, peaked at 600 microV 1 h later, and then decreased slowly down to some 300 microV after about 8 h. Gassing BSS+ with an air/5% CO2 mixture was optimal; gassing it with air reduced the TEPD values slightly, by about 10%. On the other hand, perfusion with BSS gassed with air had a rapid and marked adverse effect; the TEPD, which began at some 500 microV, fell down precipitously to about 50 microV after 1 hour. In contrast, perfusion with BSS on the endothelial side with the addition of BS to the stromal side, both sides being gassed with an air/5% CO2 mixture, maintained the TEPD at levels near those obtained with BSS+. We attribute the adverse effect by BSS to the absence of bicarbonate in it. From these and past results, we conclude that BSS cannot be recommended for intraocular use as a properly balanced saline solution.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0277-3740
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-203
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Effects of BSS and BSS+ irrigation solutions on rabbit corneal transendothelial electrical potential difference.
pubmed:affiliation
Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, New York 10032.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't