Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-6-28
pubmed:abstractText
Biomedical NMR experiments rely frequently on data obtained sequentially over time. A method is presented for analysis of time based NMR data, which allows modelling of continuous and discontinuous functions to observed intensity changes by non-linear regression and which uses variance ratio analysis to compare these models statistically. The method eliminates many of the usual problems in the parametric analysis of experimental values obtained at discrete time points and of comparison of the coefficients of model functions which require unsubstantiated assumptions about the distribution of parameters and ignore internal correlations which may exist between such parameters. The variance ratio method is illustrated for multiple time courses obtained with 23Na NMR of perfused rat kidney undergoing hypoxic perturbation in the presence of different treatments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0952-3480
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
130-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Non-linear regression and variance ratio analysis of time based NMR data.
pubmed:affiliation
Department of Medicine, University of Queensland, Brisbane, Australia.
pubmed:publicationType
Journal Article, Comparative Study