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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1977-5-25
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pubmed:abstractText |
Open-field activity was measured in female mongolian gerbils treated with pentobarbital, P-barb. (15 and 20 mg/kg) or diazepam, DZP (2,4 and 8 mb/kg), either when given singly or in combination with the analeptic bemegride, BMG (20 and 40 mg/kg). The results indicated that the addition of BMG normalized certain behaviors of the gerbils treated with P-barb. and DZP. The median effective doses of BMG in inducing convulsion and death respectively were 12.0 mg/kg and 22.5 mg/kg. A mutual antagonism is apparent since no animal died after treatment with the drug combinations and seizure activity was also very much reduced.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0301-4533
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
225
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-97
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:849067-Animals,
pubmed-meshheading:849067-Behavior, Animal,
pubmed-meshheading:849067-Bemegride,
pubmed-meshheading:849067-Body Temperature,
pubmed-meshheading:849067-Diazepam,
pubmed-meshheading:849067-Drug Interactions,
pubmed-meshheading:849067-Female,
pubmed-meshheading:849067-Gerbillinae,
pubmed-meshheading:849067-Grooming,
pubmed-meshheading:849067-Motor Activity,
pubmed-meshheading:849067-Pentobarbital,
pubmed-meshheading:849067-Seizures
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pubmed:year |
1977
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pubmed:articleTitle |
Pentobarbital, diazepam and bemegride: their effects on open-field behavior in the gerbil (Meriones unguiculatus).
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pubmed:publicationType |
Journal Article
|