Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1993-6-7
pubmed:abstractText
We describe seven cases of thrombosis of the portal and splenic vein after elective splenectomy. The diagnosis was initially unrecognized in all patients and was confused with biliary sepsis (three cases), postoperative pancreatitis (three cases), or pulmonary emboli (one case). Two patients in whom the diagnosis of portal vein thrombosis was not made within 3 days of disease onset died. In the five survivors, the diagnosis was based on clinical suspicion, confirmed with color flow Doppler ultrasonography or computed tomography with intravenous contrast material, and treated with thrombolytic agents, anticoagulants, and antibiotics. In two patients, splenic vein thrombus was visualized on initial postoperative imaging studies and the thrombus subsequently extended into the portal vein. Portal vein thrombosis should be considered in patients with fever and abdominal complaints after splenectomy. Urgent treatment with thrombolysis and anticoagulants may preserve bowel integrity and be lifesaving.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0004-0010
pubmed:author
pubmed:issnType
Print
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
565-9; discussion 569-70
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:8489390-Aged, pubmed-meshheading:8489390-Anemia, pubmed-meshheading:8489390-Diagnosis, Differential, pubmed-meshheading:8489390-Female, pubmed-meshheading:8489390-Humans, pubmed-meshheading:8489390-Male, pubmed-meshheading:8489390-Mesenteric Veins, pubmed-meshheading:8489390-Middle Aged, pubmed-meshheading:8489390-Pancreatitis, pubmed-meshheading:8489390-Pancytopenia, pubmed-meshheading:8489390-Portal Vein, pubmed-meshheading:8489390-Retrospective Studies, pubmed-meshheading:8489390-Splenectomy, pubmed-meshheading:8489390-Splenic Vein, pubmed-meshheading:8489390-Streptokinase, pubmed-meshheading:8489390-Survival Rate, pubmed-meshheading:8489390-Syndrome, pubmed-meshheading:8489390-Thrombolytic Therapy, pubmed-meshheading:8489390-Thrombosis, pubmed-meshheading:8489390-Tomography, X-Ray Computed
pubmed:year
1993
pubmed:articleTitle
Portal vein thrombosis after elective splenectomy. An underappreciated, potentially lethal syndrome.
pubmed:affiliation
Department of Surgery, Massachusetts General Hospital, Boston 02114.
pubmed:publicationType
Journal Article