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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-6-7
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pubmed:abstractText |
Erythropoietin (EPO) is highly efficacious in the treatment of the anemia of chronic renal failure. Evidence for a reported serious side effect, increased dialysis graft thrombosis, is equivocal. Sixty-four hemodialysis patients utilizing polytetrafluoroethylene (PTFE) grafts were treated with EPO. The patients served as their own historical controls. There were 1.188 thrombectomies and 0.222 mechanical problems per 1,000 patient-days prior to the initiation of EPO treatment. With EPO, the values were 0.656 and 0.222, respectively. Patients were separated into low-, medium-, and high-dose EPO groups and analyzed within groups for the effect of EPO and between groups for a dose-dependent response. According to an analysis of variance procedure, there was no statistically significant differences between the groups, which suggests that EPO is not thrombogenic to dialysis grafts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0002-9610
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
165
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
650-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8488954-Anemia,
pubmed-meshheading:8488954-Blood Vessel Prosthesis,
pubmed-meshheading:8488954-Erythropoietin,
pubmed-meshheading:8488954-Female,
pubmed-meshheading:8488954-Hematocrit,
pubmed-meshheading:8488954-Humans,
pubmed-meshheading:8488954-Kidney Failure, Chronic,
pubmed-meshheading:8488954-Male,
pubmed-meshheading:8488954-Middle Aged,
pubmed-meshheading:8488954-Platelet Count,
pubmed-meshheading:8488954-Polytetrafluoroethylene,
pubmed-meshheading:8488954-Recombinant Proteins,
pubmed-meshheading:8488954-Renal Dialysis,
pubmed-meshheading:8488954-Thrombosis
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pubmed:year |
1993
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pubmed:articleTitle |
Does the use of erythropoietin in hemodialysis patients increase dialysis graft thrombosis rates?
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pubmed:affiliation |
Department of Surgery, Good Samaritan Hospital and Medical Center, Portland, OR.
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pubmed:publicationType |
Journal Article
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