Linked Life Data

848477

Source:http://linkedlifedata.com/resource/pubmed/id/848477

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-5-12
pubmed:abstractText
In epidemiology the concepts of relative and attributable risk are used to describe the statistical association between the incidence of a disease and the presence of possible risk factors. If the association is due to a cause-effect relationship, the attributable risk can be considered as an estimate for the reduction in incidence as a consequences of intervention. In order to get unbiased estimates these risks must be standardized for the influence of confounding variables. From data of the Framingham Study these risks, standardized for the confounding influence of age, are estimated for three risk factors related to the incidence of coronary heart disease (CHD)--hypertension, hypercholesterolemia and cigarette-smoking--both marginally and jointly. Under very optimistic assumptions a theoretical reduction in 12-year CHD incidence of a maximum of about 20% is estimated from the male Framingham sample by assumedly lowering systolic blood pressure and serum cholesterol. If only cigarette-smoking could be totally eliminated, the reduction is estimated at about 37%.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-9262
pubmed:author
pubmed:issnType
Print
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Estimation of the possible effect of interventive measures in the area of ischemic heart diseases by the attributable risk percentage.
pubmed:publicationType
Journal Article