Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-5-12
pubmed:abstractText
An improved extraction method was used to obtain hypotensive principles from seeds of Gardenia jasminoides Ellis (Rubiaceae). The crude extract contained mainly glycosides and had minimal direct cardiac depressant effects. The hypotensive action was attributable to a reflex phenomenon, involving both the parasympathetic and the sympathetic vasomotor centers. It was shown that the hypotensive and bradycardiac properties of Gardenia extract were entirely abolished in a tropinized and vagotomized rats, but only partially attenuated in carotid sinus denervated rats, and that low cervical spinal transection in rats did not inhibit the hypotensive responses. Accordingly, the afferent limb of this cardiovascular reflex are consisted of both vagus nerves and baroreceptor afferents, whereas the vagi alone constituted the efferent limb.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0090-2942
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-7
pubmed:dateRevised
2005-6-14
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Phytochemical properties and hypotensive mechanism of extracts from Gardenia jasminoides seeds.
pubmed:publicationType
Journal Article