Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-6-3
pubmed:abstractText
1. 2,3,7,8-Tetrabromodibenzodioxin was administered to bile-duct-cannulated rats in a single oral dose. 2. The compound was metabolized in the liver and metabolites were secreted into the bile. 3. Several phenolic metabolites were identified as their methyl ether derivatives by gas chromatography-mass spectrometry after clean-up and methylation of bile samples. 4. The main metabolites were formed by aromatic hydroxylation and via displacement of Br-substituents (hydrolytic debromination). 5. Trace amounts of unmetabolized TBDD were also present in the bile.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0049-8254
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-26
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The metabolism of 2,3,7,8-tetrabromodibenzodioxin in the rat.
pubmed:affiliation
Research Institute of Toxicology, University of Utrecht, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't