| pubmed-article:8484102 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0021756 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0034819 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0041221 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:8484102 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:8484102 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:8484102 | pubmed:dateCreated | 1993-5-28 | lld:pubmed |
| pubmed-article:8484102 | pubmed:abstractText | We have studied the expression of IFN-gamma, IL-2 and IL-2 receptor (IL-2R) at the mRNA and protein levels in spleen and lymph node cells from Trypanosoma cruzi-infected BALB/c mice. At 21 days post infection (dpi) (peak of parasitaemia), spleen cells stimulated with Con A for 16 h showed a reduced IFN-gamma, IL-2 and IL-2R mRNA production compared with non-infected controls. Lymph node cells obtained at 4, 21 or 60 dpi produced similar amounts of IFN-gamma, IL-2 or IL-2R transcripts after mitogen stimulation as uninfected controls. Spleen cells obtained at 21 dpi showed a lower Con A proliferative response and IL-2R expression compared with non-infected controls, while the proliferation and IL-2R expression of lymph node cells at 21 dpi was unaltered. Supernatants from 48 h Con A-stimulated spleen and lymph node cells from mice at 21 dpi had very low levels of IL-2 but contained significantly higher levels of IFN-gamma compared with the supernatants of cells from non-infected mice. The latter phenomenon correlates with an accelerated rate of IFN-gamma mRNA accumulation. | lld:pubmed |
| pubmed-article:8484102 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8484102 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8484102 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8484102 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8484102 | pubmed:month | May | lld:pubmed |
| pubmed-article:8484102 | pubmed:issn | 0300-9475 | lld:pubmed |
| pubmed-article:8484102 | pubmed:author | pubmed-author:OrrEE | lld:pubmed |
| pubmed-article:8484102 | pubmed:author | pubmed-author:RottenbergM... | lld:pubmed |
| pubmed-article:8484102 | pubmed:author | pubmed-author:LeanderssonTT | lld:pubmed |
| pubmed-article:8484102 | pubmed:author | pubmed-author:SunnemarkDD | lld:pubmed |
| pubmed-article:8484102 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8484102 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:8484102 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8484102 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8484102 | pubmed:pagination | 559-68 | lld:pubmed |
| pubmed-article:8484102 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
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| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
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| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
| pubmed-article:8484102 | pubmed:meshHeading | pubmed-meshheading:8484102-... | lld:pubmed |
| pubmed-article:8484102 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8484102 | pubmed:articleTitle | Organ-specific regulation of interferon-gamma, interleukin-2 and interleukin-2 receptor during murine infection with Trypanosoma cruzi. | lld:pubmed |
| pubmed-article:8484102 | pubmed:affiliation | Department of Immunology, Karolinska Institute, Stockholm, Sweden. | lld:pubmed |
| pubmed-article:8484102 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8484102 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8484102 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8484102 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8484102 | lld:pubmed |
