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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-5-28
|
| pubmed:abstractText |
A measles outbreak in early 1989 among approximately 4200 students at a high school and two intermediate schools in suburban Houston, TX, was investigated to evaluate reasons for vaccine failure and to predict the efficacy of a booster dose of measles vaccine. Seventy-seven cases occurred (71 at the high school, 6 at intermediate schools; attack rate, 3.2 and 0.3%, respectively). Vaccination in the first year of life an 13 to 14 years since last vaccination were independent risk factors for being a case. Forty-three (18%) of 239 sera collected from students just before revaccination during the outbreak were negative by enzyme immunoassay; a neutralization assay confirmed these 43 lacked antibody predicting protection against measles infection. Of 43 enzyme immunoassay-negative students 24 gave another blood sample 9 to 10 months after revaccination. Revaccination appeared to reduce the portion of all students with neutralization titers predicting susceptibility to measles illness with rash from 7.9% to 3.0% and left the portion predicted to be susceptible to illness without rash unchanged (45%).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0891-3668
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
292-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8483623-Adolescent,
pubmed-meshheading:8483623-Antibodies, Viral,
pubmed-meshheading:8483623-Chi-Square Distribution,
pubmed-meshheading:8483623-Disease Outbreaks,
pubmed-meshheading:8483623-Disease Susceptibility,
pubmed-meshheading:8483623-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8483623-Female,
pubmed-meshheading:8483623-Humans,
pubmed-meshheading:8483623-Immunization, Secondary,
pubmed-meshheading:8483623-Male,
pubmed-meshheading:8483623-Measles,
pubmed-meshheading:8483623-Neutralization Tests,
pubmed-meshheading:8483623-Prevalence,
pubmed-meshheading:8483623-Risk Factors,
pubmed-meshheading:8483623-Schools,
pubmed-meshheading:8483623-Seasons,
pubmed-meshheading:8483623-Seroepidemiologic Studies,
pubmed-meshheading:8483623-Suburban Population,
pubmed-meshheading:8483623-Vaccination
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Investigation of a measles outbreak in a fully vaccinated school population including serum studies before and after revaccination.
|
| pubmed:affiliation |
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
|
| pubmed:publicationType |
Journal Article
|