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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-6-1
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pubmed:abstractText |
Historically, lentigo maligna melanoma has been considered a "favorable" histological type of melanoma, and treatment by wide local excision was considered curative. A retrospective multivariate analysis of 143 head and neck patients with stage I lentigo maligna melanoma was performed from a database of 1067 head and neck patients followed at Duke Medical Center. Fifty-six percent of all lentigo maligna melanomas presented with lesions deeper than 0.76 mm, and 8% presented with stage II or III disease. Recurrent disease occurred in 45% of stage I patients, with a 5-year disease-free interval of 6 years and a median survival time of 10 years. Multivariate analysis demonstrated no significant difference in disease-free interval or survival by histological subtype. The data suggest that treatment should be based on tumor thickness and not histologic subtype.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0023-852X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
520-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8483369-Adult,
pubmed-meshheading:8483369-Female,
pubmed-meshheading:8483369-Head and Neck Neoplasms,
pubmed-meshheading:8483369-Humans,
pubmed-meshheading:8483369-Male,
pubmed-meshheading:8483369-Melanoma,
pubmed-meshheading:8483369-Middle Aged,
pubmed-meshheading:8483369-Retrospective Studies,
pubmed-meshheading:8483369-Survival Rate
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pubmed:year |
1993
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pubmed:articleTitle |
Lentigo maligna melanoma of the head and neck.
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pubmed:affiliation |
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
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pubmed:publicationType |
Journal Article
|