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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
|
pubmed:dateCreated |
1993-5-21
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pubmed:abstractText |
Irregular disfiguring skin hyperpigmentation due to inflammation may develop in black persons. We investigated the treatment of this hyperpigmentation with topical tretinoin (0.1 percent retinoic acid cream). Fifty-four subjects completed a 40-week randomized, double-blind, vehicle-controlled study. Twenty-four subjects applied tretinoin daily to the face, arms, or both areas, and 30 subjects applied vehicle cream. At base line and after 40 weeks of treatment, each subject's post-inflammatory hyperpigmented lesions and normal skin were assessed by clinical and colorimetric evaluations and by analysis of biopsy specimens.
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pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0028-4793
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
20
|
pubmed:volume |
328
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1438-43
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8479462-Administration, Cutaneous,
pubmed-meshheading:8479462-Adult,
pubmed-meshheading:8479462-African Continental Ancestry Group,
pubmed-meshheading:8479462-Dermatitis,
pubmed-meshheading:8479462-Double-Blind Method,
pubmed-meshheading:8479462-Female,
pubmed-meshheading:8479462-Humans,
pubmed-meshheading:8479462-Hyperpigmentation,
pubmed-meshheading:8479462-Male,
pubmed-meshheading:8479462-Middle Aged,
pubmed-meshheading:8479462-Skin,
pubmed-meshheading:8479462-Tretinoin
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pubmed:year |
1993
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pubmed:articleTitle |
Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients.
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pubmed:affiliation |
Department of Dermatology, University of Michigan Medical Center, Ann Arbor 48109-0314.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|