rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1993-5-18
|
pubmed:abstractText |
We tested a new hormone replacement formulation based on the hypothesis that interrupted administration of progestin in the presence of continuous estrogen would result in receptor up-regulation and resensitization of target tissues to both estrogen and progestin. As a result, symptom control might be possible with lower doses of steroids and in the absence of withdrawal bleeding.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0002-9378
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
168
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1188-94; discussion 1194-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8475965-Adult,
pubmed-meshheading:8475965-Blood Pressure,
pubmed-meshheading:8475965-Body Weight,
pubmed-meshheading:8475965-Climacteric,
pubmed-meshheading:8475965-Drug Therapy, Combination,
pubmed-meshheading:8475965-Endometrium,
pubmed-meshheading:8475965-Estradiol Congeners,
pubmed-meshheading:8475965-Estrogen Replacement Therapy,
pubmed-meshheading:8475965-Estrone,
pubmed-meshheading:8475965-Female,
pubmed-meshheading:8475965-Humans,
pubmed-meshheading:8475965-Lipids,
pubmed-meshheading:8475965-Menopause,
pubmed-meshheading:8475965-Menstruation,
pubmed-meshheading:8475965-Middle Aged,
pubmed-meshheading:8475965-Patient Compliance,
pubmed-meshheading:8475965-Pilot Projects,
pubmed-meshheading:8475965-Progestins
|
pubmed:year |
1993
|
pubmed:articleTitle |
Estrogen and interrupted progestin: a new concept for menopausal hormone replacement therapy.
|
pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Toronto, Ontario, Canada.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|