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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Suppl
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pubmed:dateCreated |
1993-5-14
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pubmed:abstractText |
Serum phospholipid eicosapentaenoic (PL-EPA) and docosahexaenoic acid (PL-DHA) concentrations are associated with the dietary intake of omega 3 fatty acids. PL-EPA and PL-DHA concentrations measured 4 y apart in 211 diabetic patients were highly correlated, with Spearman correlation coefficients of 0.49 (p = 0.0001) and 0.64 (p = 0.0001), respectively. PL-DHA was positively associated with Bayley psychomotor and mental developmental indexes (PDI and MDI, respectively) in preterm infants. Using multiple-regression analysis, 64% (R2 = 0.639; p = 0.0001) of PDI variance was explained by 1/DHA and weight at 1 y, whereas 82% (R2 = 0.816; p = 0.0001) of MDI variance was explained by weight at 1 y, Apgar score, 1/DHA, and 1/EPA. 1/DHA was negatively correlated with PDI and MDI, whereas 1/EPA was positively correlated with MDI. The results suggest that infant formulas should contain preformed DHA, and that a too-high supply of EPA in addition to DHA might be harmful in preterm infants.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
801S-805S; discussion 805S-806
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8475898-Adult,
pubmed-meshheading:8475898-Child, Preschool,
pubmed-meshheading:8475898-Child Development,
pubmed-meshheading:8475898-Diabetes Mellitus,
pubmed-meshheading:8475898-Docosahexaenoic Acids,
pubmed-meshheading:8475898-Eicosapentaenoic Acid,
pubmed-meshheading:8475898-Fatty Acids, Omega-3,
pubmed-meshheading:8475898-Humans,
pubmed-meshheading:8475898-Infant, Low Birth Weight,
pubmed-meshheading:8475898-Infant, Newborn,
pubmed-meshheading:8475898-Phospholipids,
pubmed-meshheading:8475898-Psychomotor Performance
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pubmed:year |
1993
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pubmed:articleTitle |
Omega-3 fatty acids: essential fatty acids with important biological effects, and serum phospholipid fatty acids as markers of dietary omega 3-fatty acid intake.
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pubmed:affiliation |
Department of Clinical Chemistry, University Hospital of Trondheim, Norway.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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