Linked Life Data

8475716

Source:http://linkedlifedata.com/resource/pubmed/id/8475716

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-5-17
pubmed:abstractText
Further evaluation of a method suitable for investigation of toxic drug effect was performed. Rabbit corneas kept in organ culture were exposed to gentamicin for 24 h, and their weights were recorded. The weight increase observed in all specimens was significantly higher (p < 0.0001) in the corneas exposed to gentamicin 0.6 mg/ml (n = 7) than in the controls (n = 14). This was not the case for the corneas exposed to 0.3 mg/ml and 0.1 mg/ml. The accuracy of each weight recording was tested by repeated recordings. The standard deviation (SD) was less than 1%, and there was no significant difference between series performed by two different recorders. The reproducibility of the test was focused upon by calculating the SD of the control group, and by comparing the present results with the results of a control group in a recently published study (Medin 1992). The SD was approximately 2.8%, and no significant difference was found.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0001-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Further evaluation of a method used for investigation of toxic drug effects. Effect of gentamicin on rabbit corneal endothelium.
pubmed:affiliation
University Eye Department, Rikshospitalet, University of Oslo, Norway.
pubmed:publicationType
Journal Article