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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
1993-5-20
|
| pubmed:abstractText |
Although lung scanning has been performed for nearly 3 decades, the diagnosis of pulmonary embolism (PE) still remains problematic. Only about 20% of all autopsy proven cases of PE have been diagnosed during life time. Biello, and later authors of the PIOPED study defined 3 probability levels for perfusion/ventilation (inhalation) scan interpretation in comparison with pulmonary angiography: High probability (about 90% PE), indeterminate (27 to 50% PE) and low probability (about 5% PE). If the scan results are in the high and low probability group, the diagnostic procedure can be stopped. However, in the indeterminate group including 36 to 52% of all patients, diagnosis should be confirmed by pulmonary angiography. This diagnostic procedure is not well accepted by clinicians, only 0 to 15% of all patients suspected of PE undergo angiography. The diagnostic problem is more complicated due to the large amount of clinically silent PE (39 to 59% of all PE). The inclusion of the diagnosis of thrombosis ("thromboembolism") into the diagnosis of PE increases the pre-test probability for PE to 55 to 60% (= prevalence of PE in patients with deep vein thrombosis). According to Bayes' theorem, the post test probability then exceeds 95%. Without considering thrombosis, the pre-test probability is very low and therefore the post-test probability of a pathologic scan is markedly lower than 50%.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0303-8173
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
32-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1993
|
| pubmed:articleTitle |
[Diagnosis of lung embolism].
|
| pubmed:affiliation |
Ludwig-Boltzmann-Institut für Nuklearmedizin, Wilhelminenspital, Wien.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|