Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1993-5-18
|
pubmed:abstractText |
HLA haplotypes were studied in 41 unrelated families from North India with multiple cases of rheumatoid arthritis. Affected sibpairs shared parental HLA haplotypes more often than expected (chi 2 = 13.6) according to Mendelian segregation. Using the method of sibpair ratio, nonrandom segregation of parental haplotypes was observed among affected sibs. HLA-DR4 was observed in 70% of the probands while among DR4 negative probands, DR10 occurred more frequently. However no specific haplotypic association with the disease was observed in these families.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0315-162X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
253-8
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:8474060-Adult,
pubmed-meshheading:8474060-Arthritis, Rheumatoid,
pubmed-meshheading:8474060-Female,
pubmed-meshheading:8474060-HLA Antigens,
pubmed-meshheading:8474060-HLA-DQ Antigens,
pubmed-meshheading:8474060-HLA-DR Antigens,
pubmed-meshheading:8474060-Haplotypes,
pubmed-meshheading:8474060-Histocompatibility Testing,
pubmed-meshheading:8474060-Humans,
pubmed-meshheading:8474060-India,
pubmed-meshheading:8474060-Male,
pubmed-meshheading:8474060-Middle Aged,
pubmed-meshheading:8474060-Pedigree
|
pubmed:year |
1993
|
pubmed:articleTitle |
Immunogenetics of familial rheumatoid arthritis: a study of 41 multicase families.
|
pubmed:affiliation |
Histocompatibility and Immunogenetics Unit, All India Institute of Medical Sciences, New Delhi.
|
pubmed:publicationType |
Journal Article
|