Linked Life Data

8473378

Source:http://linkedlifedata.com/resource/pubmed/id/8473378

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-5-18
pubmed:abstractText
Acute exposure to bright light at night reduces the nocturnal decline of core body temperature (cBT) and inhibits melatonin secretion in men. Since inhibition of melatonin secretion by beta-adrenergic blockade reduces the nocturnal decline of cBT by 40% in women, experiments were performed to investigate whether the thermoregulatory effect of light is mediated by modifications of melatonin secretion in cycling women. Results show that the elevation of cBT induced by nocturnal exposure to bright light (3000 lux) can be reversed completely by circumventing the decline of serum melatonin levels with concurrent oral administration of melatonin. Our finding establishes melatonin as the mediator of the effect of light on cBT in women and provides a rationale for the use of orally administered melatonin as an aid in the reentrainment of the cBT rhythm in desynchronized conditions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-972X
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1036-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The effect of light on core body temperature is mediated by melatonin in women.
pubmed:affiliation
Department of Reproductive Medicine, University of California-San Diego School of Medicine, La Jolla 92093-0802.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.