| pubmed-article:8472738 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C0021270 | lld:lifeskim |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C1705480 | lld:lifeskim |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:8472738 | lifeskim:mentions | umls-concept:C0205099 | lld:lifeskim |
| pubmed-article:8472738 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8472738 | pubmed:dateCreated | 1993-5-19 | lld:pubmed |
| pubmed-article:8472738 | pubmed:abstractText | The neurohypophyseal peptide hormone arginine-vasopressin functions as a neuropeptide in several brain areas in addition to its role as a posterior pituitary hormone. Several studies indicate that arginine-vasopressin and arginine-vasopressin receptors appear early in the infant rat brain. To determine if arginine-vasopressin receptors in the infant were responsive to exogenous peptides, we compared the behavioral effects of central or peripheral administration of arginine-vasopressin, arginine vasotocin, the oxytocin precursor oxytocin-Gly-Lys-Arg, and arginine-vasopressin receptor antagonists in socially isolated rat pups. Central administration of arginine-vasopressin decreased the number of rat pup ultrasonic vocalizations, reduced locomotor activity and decreased the latency to express a response to negative geotaxis. Temperature was also reduced at all doses tested. Co-administration of arginine-vasopressin and receptor antagonists suggested that changes in vocal behavior were mediated by the V1 receptor subtype. Changes in core temperature appeared to be mediated by a V2 receptor subtype. Peripheral arginine-vasopressin administration increased calling and decreased core body temperature. Neither effect was blocked by central receptor antagonist administration. The results are consistent with the hypothesis that arginine-vasopressin receptors in the infant rat brain are functional. | lld:pubmed |
| pubmed-article:8472738 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8472738 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8472738 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8472738 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8472738 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8472738 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8472738 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8472738 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8472738 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:8472738 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:8472738 | pubmed:author | pubmed-author:InselT RTR | lld:pubmed |
| pubmed-article:8472738 | pubmed:author | pubmed-author:WinslowJ TJT | lld:pubmed |
| pubmed-article:8472738 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8472738 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:8472738 | pubmed:volume | 233 | lld:pubmed |
| pubmed-article:8472738 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8472738 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8472738 | pubmed:pagination | 101-7 | lld:pubmed |
| pubmed-article:8472738 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:meshHeading | pubmed-meshheading:8472738-... | lld:pubmed |
| pubmed-article:8472738 | pubmed:year | 1993 | lld:pubmed |
| pubmed-article:8472738 | pubmed:articleTitle | Effects of central vasopressin administration to infant rats. | lld:pubmed |
| pubmed-article:8472738 | pubmed:affiliation | Unit Develop Biopsych, NIMH, NIHAC, Poolesville, MD 20837. | lld:pubmed |
| pubmed-article:8472738 | pubmed:publicationType | Journal Article | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8472738 | lld:pubmed |
