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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1993-5-10
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pubmed:abstractText |
We evaluated the efficacy of ciprofloxacin (3 mg/ml) as the sole topical antibiotic used to treat infectious keratitis in 14 patients. We compared the ciprofloxacin-treated group to a retrospective control group of 30 consecutive culture-positive patients treated with conventional therapy in which cefazolin (50 mg/ml) and fortified gentamicin sulfate (9.1 mg/ml) solutions were used. We found no remarkable difference between the control group and the ciprofloxacin-treated group regarding patient age, risk factors, need for hospitalization, and virulence of organism isolated. The average time to healing in culture-positive ciprofloxacin-treated patients was 34 +/- 33 days vs 45 +/- 71 days in the control group and this difference was not statistically significant. The duration of antibiotic therapy in the culture-positive ciprofloxacin-treated group was 27 +/- 15 days vs 33 +/- 50 days in the control group. Four of the 30 control patients required modification of their antibiotic regimen, whereas no ciprofloxacin-treated patient required a change. Ciprofloxacin appears to be an effective single agent in the treatment of ulcerative keratitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0002-9394
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
115
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
471-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8470719-Adult,
pubmed-meshheading:8470719-Aged,
pubmed-meshheading:8470719-Aged, 80 and over,
pubmed-meshheading:8470719-Bacterial Infections,
pubmed-meshheading:8470719-Cefazolin,
pubmed-meshheading:8470719-Ciprofloxacin,
pubmed-meshheading:8470719-Corneal Ulcer,
pubmed-meshheading:8470719-Drug Therapy, Combination,
pubmed-meshheading:8470719-Eye Infections, Bacterial,
pubmed-meshheading:8470719-Female,
pubmed-meshheading:8470719-Gentamicins,
pubmed-meshheading:8470719-Humans,
pubmed-meshheading:8470719-Male,
pubmed-meshheading:8470719-Middle Aged,
pubmed-meshheading:8470719-Prospective Studies,
pubmed-meshheading:8470719-Retrospective Studies
|
pubmed:year |
1993
|
pubmed:articleTitle |
Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of ulcerative keratitis.
|
pubmed:affiliation |
Krieger Eye Institute, Sinai Hospital of Baltimore, MD 21215.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports,
Multicenter Study
|