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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-5-12
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pubmed:abstractText |
Palisaded, encapsulated neuroma (PEN) has been described as a predominantly solitary, nodular tumor; plexiform or multinodular growth patterns have not been reported in detail. We reviewed 55 PEN in order to evaluate: 1) the predominant growth patterns; 2) features that may indicate previous trauma; and 3) association with acne-like changes. Sixteen cases (29%) had growth patterns other than the solitary, nodular type. These patterns were: a) plexiform (7/16), b) multinodular (5/16), and c) fungating (4/16). Other unusual features included evidence of trauma, i.e., fibrosis, myxoid change, chronic inflammation (5/16), partially incomplete capsule (6/16), and association with acne-like features (13/16). These results suggest that: 1) plexiform or multinodular growth patterns occur relatively often in PEN; 2) some changes indicate a possible histogenetic relation to traumatic neuroma, probably via secondary traumatization; 3) a high frequency of association with acne-like changes which could imply, but does not prove, an acne-induced histogenesis; and 4) the differential diagnosis of cutaneous plexiform lesions should include PEN.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0303-6987
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8468415-Acne Vulgaris,
pubmed-meshheading:8468415-Adult,
pubmed-meshheading:8468415-Aged,
pubmed-meshheading:8468415-Antigens, Neoplasm,
pubmed-meshheading:8468415-Collagen,
pubmed-meshheading:8468415-Female,
pubmed-meshheading:8468415-Humans,
pubmed-meshheading:8468415-Immunohistochemistry,
pubmed-meshheading:8468415-Male,
pubmed-meshheading:8468415-Membrane Glycoproteins,
pubmed-meshheading:8468415-Middle Aged,
pubmed-meshheading:8468415-Mucin-1,
pubmed-meshheading:8468415-Neurofibroma,
pubmed-meshheading:8468415-Neuroma,
pubmed-meshheading:8468415-Wounds and Injuries
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pubmed:year |
1993
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pubmed:articleTitle |
Plexiform and other unusual variants of palisaded encapsulated neuroma.
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pubmed:affiliation |
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City 52242-1009.
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pubmed:publicationType |
Journal Article
|