pubmed-article:8464479 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C1333663 | lld:lifeskim |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C1530719 | lld:lifeskim |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C0039597 | lld:lifeskim |
pubmed-article:8464479 | lifeskim:mentions | umls-concept:C2827370 | lld:lifeskim |
pubmed-article:8464479 | pubmed:issue | 6419 | lld:pubmed |
pubmed-article:8464479 | pubmed:dateCreated | 1993-4-30 | lld:pubmed |
pubmed-article:8464479 | pubmed:abstractText | The transcription factor GATA-1 is a fundamental regulator of genes in haematopoietic cell lineages and belongs to a family of factors that bind to the consensus sequence WGATAR. The GATA motif was originally identified in cis-regulatory regions of globin and other erythroid-specific genes, but the range of genes controlled by the GATA factors has since expanded. Members of the GATA transcription factor family share a conserved zinc-finger DNA-binding domain, but the expression profile of each GATA factor is distinct. Here we show that a testis form of murine (m)GATA-1 messenger RNA is transcribed from a promoter located 5' to the erythroid first exon, and the remaining exons (which encode the mGATA-1 protein) are used in common by both testis and erythroid transcripts. We use an anti-mGATA-1 monoclonal antibody to show that the factor expressed in erythroid cells is the same as that found in the seminiferous tubules of murine testis. The GATA-1-expressing cells in 10-week-old testis were found only in contact with the basement membrane of seminiferous tubules, suggesting that GATA-1 regulates genes during the earliest stages of spermatogenesis. | lld:pubmed |
pubmed-article:8464479 | pubmed:language | eng | lld:pubmed |
pubmed-article:8464479 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8464479 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8464479 | pubmed:month | Apr | lld:pubmed |
pubmed-article:8464479 | pubmed:issn | 0028-0836 | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:YamamotoMM | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:IshiharaHH | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:ItoEE | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:YokoyamaMM | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:EngelJ DJD | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:OhtaniHH | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:JL | lld:pubmed |
pubmed-article:8464479 | pubmed:author | pubmed-author:TokiTT | lld:pubmed |
pubmed-article:8464479 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8464479 | pubmed:day | 1 | lld:pubmed |
pubmed-article:8464479 | pubmed:volume | 362 | lld:pubmed |
pubmed-article:8464479 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8464479 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8464479 | pubmed:pagination | 466-8 | lld:pubmed |
pubmed-article:8464479 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8464479 | pubmed:meshHeading | pubmed-meshheading:8464479-... | lld:pubmed |
pubmed-article:8464479 | pubmed:year | 1993 | lld:pubmed |
pubmed-article:8464479 | pubmed:articleTitle | Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. | lld:pubmed |
pubmed-article:8464479 | pubmed:affiliation | Department of Pediatrics, Hirosaki University School of Medicine, Japan. | lld:pubmed |
pubmed-article:8464479 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8464479 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:8464479 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:8464479 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:14460 | entrezgene:pubmed | pubmed-article:8464479 | lld:entrezgene |
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