Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-5-4
pubmed:abstractText
Indium-111 oxine labelled leucocyte (111In oxine leucocyte) scintigraphy is the test of choice in detecting occult infection and localising focal inflammation. 111In oxine labelling is technically difficult and expensive and leucocyte labelling with technetium-99m stannous colloid (99mTc Sn colloid) has been considered to be an alternative. Leucocytes from 40 cases referred for investigation of occult infection or localisation of inflammation were simultaneously labelled with 111In oxine and 99mTc Sn colloid with dual isotope acquisition performed at 1, 3 and 24 h. Twenty-four hour 99mTc Sn colloid scans were corrected for 111In downscatter. Each case was independently interpreted by two experienced observers. Twenty-one patients demonstrated positive 111In oxine leucocyte scans. Using 111In oxine leucocyte scans as the gold standard, 99mTc Sn colloid leucocyte scanning had an overall sensitivity of 86% and a specificity of 95%. Clinical follow-up verified that three patients had false negative 99mTc Sn colloid leucocyte scans and one patient had a false positive. Further clinical evaluation of 99mTc Sn colloid labelled leucocytes is required before they can become a reliable replacement for 111In oxine leucocytes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0340-6997
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:8462607-Colloids, pubmed-meshheading:8462607-Evaluation Studies as Topic, pubmed-meshheading:8462607-Female, pubmed-meshheading:8462607-Focal Infection, pubmed-meshheading:8462607-Humans, pubmed-meshheading:8462607-Indium Radioisotopes, pubmed-meshheading:8462607-Inflammation, pubmed-meshheading:8462607-Leukocytes, pubmed-meshheading:8462607-Male, pubmed-meshheading:8462607-Middle Aged, pubmed-meshheading:8462607-Organometallic Compounds, pubmed-meshheading:8462607-Oxyquinoline, pubmed-meshheading:8462607-Predictive Value of Tests, pubmed-meshheading:8462607-Sensitivity and Specificity, pubmed-meshheading:8462607-Technetium, pubmed-meshheading:8462607-Technetium Compounds, pubmed-meshheading:8462607-Time Factors, pubmed-meshheading:8462607-Tin, pubmed-meshheading:8462607-Tin Compounds
pubmed:year
1993
pubmed:articleTitle
Evaluation of white cell scintigraphy using indium-111 and technetium-99m labelled leucocytes.
pubmed:affiliation
Department of Nuclear Medicine, St. George Hospital, Kogarah, Australia.
pubmed:publicationType
Journal Article, Comparative Study