Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1993-4-30
pubmed:abstractText
Using reverse transcription-polymerase chain reaction (RT-PCR), transcripts for EGF receptor and for EGF, transforming growth factor-alpha (TGF alpha), amphiregulin (AR) and heparin binding-EGF (HB-EGF) were detected in porcine corpora lutea at day 4, 10 and 20 of the estrous cycle. No cycle-dependent changes were apparent in the expression of the receptor, AR or TGF alpha. In contrast, HB-EGF mRNA levels appeared highest on day 4 during luteal growth and development, whereas EGF mRNA levels appeared highest on day 20 when the corpora lutea undergo luteolysis. These results suggest that luteal function may be subject to regulation by members of the EGF family acting in an autocrine, paracrine or intracrine manner.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1857-9
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Expression of the genes for the epidermal growth factor receptor and its ligands in porcine corpora lutea.
pubmed:affiliation
Department of Biochemistry, AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't