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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1977-5-25
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pubmed:abstractText |
Dietary lead at different dose levels was given to female C57B1 mice for periods up to 3 months. No severe chromosome or chromatid aberrations were observed at any dose level and the frequency of chromatid gaps increased significantly only at the highest doses. (0.5 and 1% of lead in the diet). The number of micronuclei in polychromatic erythrocytes also remained at control levels after lead treatment, whereas known mutagenic agent such as Myleran and Mitomycine C raised their incidence markedly. Taking into account also the data in the literature, it is concluded that lead per se probably has no mutagenic action on mammals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0098-4108
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
619-24
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:846009-Animals,
pubmed-meshheading:846009-Bone Marrow,
pubmed-meshheading:846009-Bone Marrow Cells,
pubmed-meshheading:846009-Chromosome Aberrations,
pubmed-meshheading:846009-Diet,
pubmed-meshheading:846009-Erythrocytes,
pubmed-meshheading:846009-Female,
pubmed-meshheading:846009-Lead,
pubmed-meshheading:846009-Mice,
pubmed-meshheading:846009-Mice, Inbred C57BL,
pubmed-meshheading:846009-Mutagens,
pubmed-meshheading:846009-Time Factors
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pubmed:year |
1977
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pubmed:articleTitle |
Cytogenetic investigations on mice treated with lead.
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pubmed:publicationType |
Journal Article
|