Linked Life Data

8459678

Source:http://linkedlifedata.com/resource/pubmed/id/8459678

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-4-29
pubmed:abstractText
This is the initial report of an unusually high incidence of exencephaly in inbred New Zealand White (NZW) mice and the congenic NZW-xid strain, in which animals are homozygous for the recessive X-linked immune deficiency (xid) gene. The predominant expression of exencephaly in female pups and a disproportionate decrease in numbers of female pups in litters suggested that exencephaly was part of a continuum of lethal defects expressed preferentially in females. Genetic influence in the expression of exencephaly in NZW mice was postulated because environmental cohort controls did not express this defect. NZW mice are an additional model for studying the pathogenesis of neural tube defects.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
58-60
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
New Zealand white mice: an experimental model of exencephaly.
pubmed:affiliation
Department of Pathology, College of Veterinary Medicine, University of Missouri, Columbia 65212.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.