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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-4-27
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pubmed:abstractText |
Beta-endorphin was measured in the plasma of pigs during late pregnancy and at different stages of the oestrous cycle. In pregnant animals, beta-endorphin secretion from uteroplacental tissues into the maternal circulation and the possible effects of oxytocin and the prostaglandin F2 alpha (PGF2 alpha) analogue cloprostenol on beta-endorphin release were determined. Plasma beta-endorphin concentrations in pregnant sows were significantly higher than in non-pregnant pigs. However, there were no significant changes in beta-endorphin values throughout the oestrous cycle. Because the increase in plasma beta-endorphin concentrations had occurred before luteolysis and onset of labour it could not be attributed to the stress of parturition. The surgical intervention of a laparotomy increased beta-endorphin release into peripheral plasma. Cloprostenol but not oxytocin caused an immediate increase in plasma beta-endorphin concentrations. At parturition, endogenous PGF2 alpha may be involved in the regulation of beta-endorphin secretion. Concentrations of beta-endorphin in the jugular and uterine vein plasma were not significantly different, and so it would appear that beta-endorphin in the plasma of pregnant sows is not of uteroplacental origin. In conclusion, changes in the concentration of beta-endorphin in peripheral plasma, associated with pregnancy but not the oestrous cycle, exist in pigs. Hence a physiological function of peripheral opioid peptides in the periparturient sow is feasible.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-0795
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-206
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8459187-Animals,
pubmed-meshheading:8459187-Cloprostenol,
pubmed-meshheading:8459187-Estrus,
pubmed-meshheading:8459187-Female,
pubmed-meshheading:8459187-Jugular Veins,
pubmed-meshheading:8459187-Oxytocin,
pubmed-meshheading:8459187-Pregnancy,
pubmed-meshheading:8459187-Pregnancy, Animal,
pubmed-meshheading:8459187-Progesterone,
pubmed-meshheading:8459187-Swine,
pubmed-meshheading:8459187-Uterus,
pubmed-meshheading:8459187-beta-Endorphin
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pubmed:year |
1993
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pubmed:articleTitle |
Beta-endorphin in sows during late pregnancy: effects of cloprostenol and oxytocin on plasma concentrations of beta-endorphin in the jugular and uterine veins.
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pubmed:affiliation |
Klinik für Geburtshilfe und Gynäkologie des Rindes, Tierärztliche Hochschule, Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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