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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-4-29
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pubmed:abstractText |
Intrastromal corneal crystals developed in 11 of 49 monkey eyes with hydrogel intracorneal lenticules followed over a 4 year period. All of the eyes, except one, underwent synthetic keratophakia via a microkeratome incision. The diagnosis of crystal formation was initially made by slit-lamp examination and confirmed with specular microscopy (from 21 to 150 days post-hydrogel keratophakia). The crystals were noted to lie in a plane adjacent to the hydrogel lenticule and specular microscopy revealed polychromatic, hyperrefringent crystals with either a rectangular or linear morphology. Prior to intrastromal crystal formation, these corneas developed early postoperative stromal edema (< 3 weeks). We hypothesize that early stromal edema in combination with the hydrogel intracorneal lenticule induced the production of lipid crystals by stromal keratocytes.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0277-3740
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-34
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8458229-Animals,
pubmed-meshheading:8458229-Corneal Diseases,
pubmed-meshheading:8458229-Corneal Edema,
pubmed-meshheading:8458229-Corneal Stroma,
pubmed-meshheading:8458229-Crystallization,
pubmed-meshheading:8458229-Hydrogel,
pubmed-meshheading:8458229-Macaca mulatta,
pubmed-meshheading:8458229-Polyethylene Glycols,
pubmed-meshheading:8458229-Prostheses and Implants
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pubmed:year |
1993
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pubmed:articleTitle |
Intrastromal crystalline deposits following hydrogel keratophakia in monkeys.
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pubmed:affiliation |
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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