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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1993-4-21
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pubmed:abstractText |
Serum antibodies against native collagen type II and cartilage proteoglycans as well as proliferative responses of spleen lymphocytes to these antigens were evidenced during the progression of antigen-induced arthritis in mice. Because there were some correlations to the severity of arthritis, it is suggested that autoimmunity to cartilage constituents play a role for the persistence of the joint inflammation and cartilage destruction in this experimental model of chronic arthritis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0379-0363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-73
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8456645-Animals,
pubmed-meshheading:8456645-Antibody Formation,
pubmed-meshheading:8456645-Arthritis, Experimental,
pubmed-meshheading:8456645-Autoimmunity,
pubmed-meshheading:8456645-Cartilage, Articular,
pubmed-meshheading:8456645-Collagen,
pubmed-meshheading:8456645-Female,
pubmed-meshheading:8456645-Immunity, Cellular,
pubmed-meshheading:8456645-Lymphocyte Activation,
pubmed-meshheading:8456645-Mice,
pubmed-meshheading:8456645-Mice, Inbred C57BL,
pubmed-meshheading:8456645-Proteoglycans,
pubmed-meshheading:8456645-Rats
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pubmed:year |
1993
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pubmed:articleTitle |
Humoral and cell-mediated sensitivity to cartilage constituents in mice with antigen-induced arthritis.
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pubmed:affiliation |
Institute of Pathology, Friedrich Schiller University, Jena, Germany.
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pubmed:publicationType |
Journal Article
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