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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5101
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pubmed:dateCreated |
1993-4-21
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pubmed:abstractText |
Betacellulin, a member of the epidermal growth factor family, has been identified in the conditioned medium of cell lines derived from mouse pancreatic beta cell tumors. Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. The carboxyl-terminal domain of betacellulin has 50 percent sequence similarity with that of rat transforming growth factor alpha. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Oligodeoxyribonucleotides,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Thymidine,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/betacellulin
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
259
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1604-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8456283-3T3 Cells,
pubmed-meshheading:8456283-Amino Acid Sequence,
pubmed-meshheading:8456283-Animals,
pubmed-meshheading:8456283-Base Sequence,
pubmed-meshheading:8456283-Cell Division,
pubmed-meshheading:8456283-Cells, Cultured,
pubmed-meshheading:8456283-DNA Replication,
pubmed-meshheading:8456283-Endothelium, Vascular,
pubmed-meshheading:8456283-Epidermal Growth Factor,
pubmed-meshheading:8456283-Growth Substances,
pubmed-meshheading:8456283-Humans,
pubmed-meshheading:8456283-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:8456283-Islets of Langerhans,
pubmed-meshheading:8456283-Kinetics,
pubmed-meshheading:8456283-Mice,
pubmed-meshheading:8456283-Molecular Sequence Data,
pubmed-meshheading:8456283-Muscle, Smooth, Vascular,
pubmed-meshheading:8456283-Oligodeoxyribonucleotides,
pubmed-meshheading:8456283-Pancreatic Neoplasms,
pubmed-meshheading:8456283-Pigment Epithelium of Eye,
pubmed-meshheading:8456283-Polymerase Chain Reaction,
pubmed-meshheading:8456283-Protein Precursors,
pubmed-meshheading:8456283-Rats,
pubmed-meshheading:8456283-Receptor, Epidermal Growth Factor,
pubmed-meshheading:8456283-Recombinant Proteins,
pubmed-meshheading:8456283-Sequence Homology, Amino Acid,
pubmed-meshheading:8456283-Thymidine,
pubmed-meshheading:8456283-Transforming Growth Factor alpha
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pubmed:year |
1993
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pubmed:articleTitle |
Betacellulin: a mitogen from pancreatic beta cell tumors.
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pubmed:affiliation |
Department of Surgery, Children's Hospital, Boston, MA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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