Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1977-5-25
pubmed:abstractText
Human and rat decalcified bone matrix preparations were shown to be active in inducing cartilage formation by subcutaneous implantation in the rat. When young rat fibroblastic cells were grown in cultures, which also contained bone matrix preprations in particulate form, the fibroblastic cells underwent a uniform and consistent morphological alteration. These altered cells showed higher rates of synthesis of hyaluronic acid and chondroitin sulfate than the controls and exhibited very active amino-sugar-nucleotide metabolism. It is suggested that this approach to the culture of connective tissue cells will allow a more precise definition of the early steps of connective tissue differentiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
781-91
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The effect of bone matrix on young connective tissue cells in culture.
pubmed:publicationType
Journal Article