Linked Life Data

8448126

Source:http://linkedlifedata.com/resource/pubmed/id/8448126

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1993-4-13
pubmed:abstractText
The rate of regeneration of bovine pancreatic ribonuclease A with oxidized and reduced dithiothreitol (DTTox and DTTred, respectively) decreases by a factor of 10 when the temperature is increased from 25 to 37 degrees C. The rate of regeneration of RNase A with oxidized and reduced glutathione increases slightly over that same range of temperature. This suggests that the regeneration processes with the two types of redox reagents proceed through different pathways. There is a significant change in the distribution of three-disulfide intermediates populated during regeneration with DTTox/DTTred over the range of temperature 15-37 degrees C that suggests that the three-disulfide species populated at 15 degrees C are directly involved in the major regeneration pathway observed at 25 degrees C.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0006-2960
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2698-703
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Regeneration of bovine pancreatic ribonuclease A. 4. Temperature dependence of the regeneration rate.
pubmed:affiliation
Baker Laboratory of Chemistry, Cornell University, Ithaca, New York 14853-1301.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't