Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1977-5-25
|
| pubmed:abstractText |
Studies of luteinizing hormone (LH)-mediated serum inhibition and of follicular fluid and granulosa cell inhibition of in vitro porcine, ewe, and cow oocyte meiotic maturation have been carried out. A porcine serum inhibitor or inhibitors with a molecular weight above 15,000, similar to the ewe and cow serum inhibitor(s), have been demonstrated. An LH-inactivated inhibitor or inhibitors in fluid from medium-sized ewe and cow follicles have been shown and a minimally effective porcine follicular fluid inhibitor has been confirmed. The estimated molecular weight of these inhibitors is below 1,000. Granulosa cells from the three species were not found to be dramatically inhibitory. It is postulated that the follicular fluid inhibitor(s) may be derived from the larger serum molecule(s) by an action of LH within an intermediate cell type.
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Animals, Laboratory,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research,
http://linkedlifedata.com/resource/pubmed/keyword/Endocrine System,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia,
http://linkedlifedata.com/resource/pubmed/keyword/Germ Cells,
http://linkedlifedata.com/resource/pubmed/keyword/Gonadotropins,
http://linkedlifedata.com/resource/pubmed/keyword/Gonadotropins, Pituitary,
http://linkedlifedata.com/resource/pubmed/keyword/Hormones,
http://linkedlifedata.com/resource/pubmed/keyword/In Vitro,
http://linkedlifedata.com/resource/pubmed/keyword/Luteinizing Hormone--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Ovum,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Reproduction,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Urogenital System
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0015-0282
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
28
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
476-81
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:otherAbstract |
PIP: The inhibitory effects of luteinizing hormone (LH)-mediated serum and of follicular fluid and granulosa cells on the in vitro oocyte meiotic maturation of sows, ewes, and cows were investigated. Oocyte meiotic maturation was delayed by a porcine serum inhibitor(s) was evident in fluid from medium-size ewe and cow follicles. A minimally effective follicular fluid inhibitor was demonstrated in sows. The molecular weights of these inhibitors was estimated to be less than 1000. Granulosa cells did not have a marked inhibitory effect in any of the 3 species. It is suggested that follicular fluid inhibitor(s) may be derived from larger serum follicles by some activity of LH within an intermediate cell type.
|
| pubmed:meshHeading |
pubmed-meshheading:844624-Animals,
pubmed-meshheading:844624-Blood,
pubmed-meshheading:844624-Body Fluids,
pubmed-meshheading:844624-Cattle,
pubmed-meshheading:844624-Female,
pubmed-meshheading:844624-Granulosa Cells,
pubmed-meshheading:844624-Luteinizing Hormone,
pubmed-meshheading:844624-Meiosis,
pubmed-meshheading:844624-Oocytes,
pubmed-meshheading:844624-Oogenesis,
pubmed-meshheading:844624-Ovarian Follicle,
pubmed-meshheading:844624-Ovum,
pubmed-meshheading:844624-Sheep,
pubmed-meshheading:844624-Swine
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Further studies of inhibitors of in vitro mammalian oocyte maturation.
|
| pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
|