Linked Life Data

8445787

Source:http://linkedlifedata.com/resource/pubmed/id/8445787

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-4-2
pubmed:abstractText
Immune function in harbor seal mothers and their pups during lactation was studied on Sable Island, Nova Scotia, Canada, during the springs of 1989 and 1990. Methods included total white blood cell and differential counts, a Protein A enzyme linked immunosorbent assay (ELISA) for total immunoglobulin G (IgG) quantification, and functionality testing of lymphocytes in vitro using the T-cell mitogen concanavalin A (ConA). Lymphocyte functionality and total IgG levels were reduced in the mothers at the end of lactation, suggesting a reduction in immune function, possibly as a result of the stress of fasting, or hormonal changes associated with lactation and estrus. By contrast, lymphocyte functionality and total IgG levels in pups were low at birth and higher at the end of lactation. Pups at birth and females late in lactation may therefore be more susceptible to infection by viral and bacterial agents. This study represents the first broad examination of immune function in a free-ranging pinniped population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0090-3558
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Immune function in free-ranging harbor seal (Phoca vitulina) mothers and their pups during lactation.
pubmed:affiliation
Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't