Linked Life Data

8445544

Source:http://linkedlifedata.com/resource/pubmed/id/8445544

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-4-6
pubmed:abstractText
The frequencies of HLA-DR and DQ antigens in 24 Chinese patients with Behçet's disease (BD) were calculated and compared with those in 130 healthy control Chinese and those in 80 Chinese patients with recurrent oral ulcers (ROU). Although an increased trend of DRw6 and DRw8 antigens in patients with BD was noted, there was no significant difference in frequencies of HLA-DR and DQ antigens between patients with BD and healthy control subjects or patients with ROU after correction of P values (Pc > 0.05). Further analysis of our data of the phenotype frequencies of DRw6 and DRw8 antigens according to the subtypes of BD also showed the increased frequencies of DRw6 and DRw8 antigens in patients with mucocutaneous type of BD as compared with those in healthy control subjects. However, only the phenotype frequency of DRw8 antigen in patients with mucocutaneous type of BD was significantly higher than that in patients with ROU (P < 0.005, Pc < 0.05, relative risk = 17.7, and etiologic fraction = 0.30). This significant increase of the phenotype frequency suggests that the gene coding for HLA-DRw8 antigen in patients with ROU was only partially (30%) responsible for susceptibility to the mucocutaneous type of BD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0904-2512
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
60-3
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
HLA-DR and DQ antigens in Chinese patients with Behçet's disease.
pubmed:affiliation
School of Dentistry, College of Medicine, National Taiwan University, Taipei, ROC.
pubmed:publicationType
Journal Article, Comparative Study