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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-4-6
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pubmed:abstractText |
Sympathetic nervous system activity as indicated by circulating norepinephrine has been demonstrated to increase with advancing chronological age both at rest and during submaximal exercise. Much of the earlier work investigating this aging phenomenon used a younger group that had a higher peak oxygen consumption (VO2) than did the older group, which made comparisons difficult. In the present study, young [n = 7, 36 +/- 1.0 (SE) yr] and old subjects (n = 8, 61 +/- 1.2 yr) were matched on peak VO2 and then exercised at approximately the same relative submaximal VO2 (75%) and power output on a cycle ergometer for 21 min. Blood samples were collected at rest and in the 7th, 14th, and last minute of a 21-min exercise bout via an indwelling catheter in an antecubital vein. The norepinephrine responses for the young and old groups, respectively, were as follows: rest, 486 +/- 111 vs. 673 +/- 108; 7 min, 1,258 +/- 255 vs. 1,185 +/- 172; 14 min, 1,639 +/- 316 vs. 1,528 +/- 288; and 21 min, 2,038 +/- 488 vs. 1,936 +/- 453 pg/ml. These responses were not significantly different between the groups at any time period. The epinephrine values for the age groups were not statistically different: rest, 115 +/- 60 vs 88 +/- 51; 7 min, 140 +/- 18 vs. 326 +/- 88; 14 min, 216 +/- 33 vs. 366 +/- 104; and 21 min, 324 +/- 100 vs. 447 +/- 113 pg/ml.(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
8750-7587
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-54
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8444733-Adult,
pubmed-meshheading:8444733-Aerobiosis,
pubmed-meshheading:8444733-Aged,
pubmed-meshheading:8444733-Aging,
pubmed-meshheading:8444733-Body Composition,
pubmed-meshheading:8444733-Epinephrine,
pubmed-meshheading:8444733-Exercise,
pubmed-meshheading:8444733-Humans,
pubmed-meshheading:8444733-Male,
pubmed-meshheading:8444733-Middle Aged,
pubmed-meshheading:8444733-Norepinephrine,
pubmed-meshheading:8444733-Oxygen,
pubmed-meshheading:8444733-Sympathetic Nervous System
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pubmed:year |
1993
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pubmed:articleTitle |
Young and old subjects matched for aerobic capacity have similar noradrenergic responses to exercise.
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pubmed:affiliation |
Department of Human Kinetics, University of Wisconsin-Milwaukee 53201.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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