Linked Life Data

8444639

Source:http://linkedlifedata.com/resource/pubmed/id/8444639

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-4-6
pubmed:abstractText
The biochemical properties, virulence for mice and trout, and the extracellular virulence factors at 28 degrees and 37 degrees C of 11 environmental and nine human strains of Aeromonas hydrophila were compared. All the environmental isolates and four of the human group were virulent for trout at 3 x 10(7) cfu, but only human strains were able to cause death or lesions in mice by the intramuscular route. Extracellular virulence factors such as haemolysins, cytotoxins and proteases were also investigated in supernatant fluids of cultures grown at 28 degrees C and 37 degrees C. The production of haemolysins, caseinases, elastases and growth yields of environmental strains decreased sharply during cultivation at 37 degrees C but cytotoxins were produced to the same extent, or slightly less, than at 28 degrees C. The human strains differed from the environmental strains in response to growth temperatures: protease activity decreased at 37 degrees C, although growth yield was not affected, but more haemolysins and cytotoxins were produced by the virulent strains at this temperature than at 28 degrees C. Sodium caseinate SDS-PAGE of culture supernatant fluids of selected human strains revealed that temperature selectively inhibited the production of certain proteases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-8847
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Influence of growth temperature on the production of extracellular virulence factors and pathogenicity of environmental and human strains of Aeromonas hydrophila.
pubmed:affiliation
Departamento de Patología Animal (Sanidad Animal), Facultad de Veterinaria, Universidad de León, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't