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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-4-8
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pubmed:abstractText |
The intellectual performance of 22 children aged 3-16 years with maple syrup urine disease (MSUD) was assessed and compared to a group of early treated phenylketonuria (PKU) children and normal subjects matched by age, sex, nationality, and socio-economic status. All subjects were tested by one examiner only using the age related versions of the non-verbal Snijders-Oomen intelligence test. The mean IQ (+/- SD) score was 74 +/- 14 (range 50-103) in patients with MSUD, 101 +/- 12 (range 87-125) in early treated PKU patients, and 107 +/- 9 (range 90-122) in normal subjects. Intercorrelations indicated that length of time after birth that plasma leucine concentration remained > 1 mmol/l and quality of long-term metabolic control have important influences on IQ.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
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pubmed:issn |
0340-6199
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
144-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8444223-Adolescent,
pubmed-meshheading:8444223-Case-Control Studies,
pubmed-meshheading:8444223-Child,
pubmed-meshheading:8444223-Child, Preschool,
pubmed-meshheading:8444223-Female,
pubmed-meshheading:8444223-Humans,
pubmed-meshheading:8444223-Intellectual Disability,
pubmed-meshheading:8444223-Intelligence,
pubmed-meshheading:8444223-Intelligence Tests,
pubmed-meshheading:8444223-Least-Squares Analysis,
pubmed-meshheading:8444223-Leucine,
pubmed-meshheading:8444223-Male,
pubmed-meshheading:8444223-Maple Syrup Urine Disease,
pubmed-meshheading:8444223-Phenylketonurias
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pubmed:year |
1993
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pubmed:articleTitle |
Intellectual performance of children with maple syrup urine disease.
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pubmed:affiliation |
Department of Paediatrics, Heinrich-Heine University, Düsseldorf, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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