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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1993-3-24
|
| pubmed:abstractText |
We have investigated the feasibility of administration of an effective dose of the hypoxic cytotoxin, SR 4233, Monday-Friday daily for 6 weeks. From a thorough hematological, histopathological and clinical chemistry evaluation throughout the course and during a 3-week recovery period, we conclude that daily administration of a radiopotentiating dose of SR 4233 in mice is well tolerated and that bone marrow suppression is likely to be the dose-limiting toxicity.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0167-8140
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
79-81
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8438092-Animals,
pubmed-meshheading:8438092-Drug Administration Schedule,
pubmed-meshheading:8438092-Female,
pubmed-meshheading:8438092-Mice,
pubmed-meshheading:8438092-Mice, Inbred Strains,
pubmed-meshheading:8438092-Radiation-Sensitizing Agents,
pubmed-meshheading:8438092-Triazines
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Toxicology of daily administration to mice of the radiation potentiator SR 4233 (WIN 59075).
|
| pubmed:affiliation |
Department of Radiation Oncology, Stanford University School of Medicine, CA 94305-5468.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|