Linked Life Data

8434149

Source:http://linkedlifedata.com/resource/pubmed/id/8434149

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-3-16
pubmed:abstractText
Mucosal and serum antibodies against Actinobacillus pleuropneumoniae serotype 2 were demonstrable in an ELISA which used whole bacterial cells as antigen. Following experimental infection of pigs with A pleuropneumoniae serotype 2, specific antibodies against the bacteria were demonstrated in saliva and fluid obtained by bronchoalveolar lavage. There was a good correlation between the IgA antibody titre in this fluid and serum. As a result of natural infection, IgA antibodies were also demonstrable in the saliva at an early stage of infection when no serum antibodies were detectable. Later in the infection, when antibodies were present in the serum, salivary IgA antibodies were undetectable. The data suggest that the mucosal IgA antibody response arises before the systemic response. Measuring mucosal antibodies in saliva or nasal or bronchoalveolar fluid might therefore open the possibility of identifying pigs infected with A pleuropneumoniae at an early stage of infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0034-5288
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Antibodies against Actinobacillus pleuropneumoniae serotype 2 in mucosal secretions and sera of infected pigs as demonstrated by an enzyme-linked immunosorbent assay.
pubmed:affiliation
Department of Clinical Studies, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't