Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-3-18
pubmed:abstractText
The dependence of spontaneous transmitter release by regenerated nerve endings on age was studied in rat extensor digitorum longus muscle after sciatic nerve crush during the first year of life. Intracellular recordings were carried out at different times after denervation in muscles of 1.5-, 3- or 12-month-old animals. The frequency of miniature endplate potentials was detected. In order to determine the percentage of multiple innervation, nerve-evoked endplate potentials were recorded. The time course of the percentage of polyinnervated muscle cells was similar in the three groups of animals, but mepp frequency increased more slowly with increasing age. Moreover, by extrapolating the intercept of linear regression for mepp frequency vs days from denervation, a conventional initial time of reinnervation may be computed: the results are consistent with a decrease in the nerve regeneration rate during the first year of life.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-510X
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-103
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Age-related changes in maturation of regenerated motor innervation.
pubmed:affiliation
Institute of Anatomy and General Physiology, University of Urbino, Italy.
pubmed:publicationType
Journal Article