Linked Life Data

8433005

Source:http://linkedlifedata.com/resource/pubmed/id/8433005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Suppl
pubmed:dateCreated
1993-3-15
pubmed:abstractText
Ellipsoid and spheroid melanosomes similar to those found in the hair matrix melanocytes of eumelanic C57BL mice and pheomelanic Ay mice, respectively, have been shown to coexist in the same human melanocyte. The difference in the three-dimensional ultrastructure of these melanosomes of the human hair matrix melanocyte has been determined by high-voltage transmission electron microscopy using a goniometer. By energy-dispersive X-ray spectroscopy, sulfur, one of the main characteristic chemical properties of pheomelanin, is detected in a significant amount in each spheroid melanosome, but is absent in ellipsoid melanosomes. Furthermore, the internal structure of the spheroid melanosomes is dissolved by treatment with 0.5 N NaOH solution, whereas the ellipsoid melanosomes are not affected. We proposed that in normal human melanocytes pheo- and eumelanogenesis occurs in spheroid and ellipsoid melanosomes, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-202X
pubmed:author
pubmed:issnType
Print
pubmed:volume
100
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172S-175S
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Detection of eumelanogenic and pheomelanogenic melanosomes in the same normal human melanocyte.
pubmed:affiliation
Department of Dermatology, Kobe University School of Medicine, Japan.
pubmed:publicationType
Journal Article