Linked Life Data

8432342

Source:http://linkedlifedata.com/resource/pubmed/id/8432342

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-3-15
pubmed:abstractText
It is known that nutritional restriction during gestation affects the growth of the corpus callosum. The present study was designed to evaluate whether prenatal malnutrition may alter, in the rat, the normal pattern of functional callosal interhemispheric connections of the visual cortex. Since callosal development has been associated with brain lateralization, the effect of malnutrition during gestation on the normal asymmetry of visual cortical evoked responses was also studied. Prenatal malnutrition was induced by restricting food consumption by pregnant rats (10 g daily) from Day 8 post-conception to parturition. Results of experiments performed on 45- to 50-day-old offspring showed that the starvation treatment (i) reduced both the peak-to-peak amplitude and the extent of the projecting field of transcallosal evoked responses, and (ii) abolished the normal brain interhemispheric asymmetry of visual evoked responses. These effects are discussed in relationship to regressive events occurring during synaptogenesis, which are known to play key roles in establishing the adult structure and functional properties of the corpus callosum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0014-4886
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Functional alterations induced by prenatal malnutrition in callosal connections and interhemispheric asymmetry as revealed by transcallosal and visual evoked responses in the rat.
pubmed:affiliation
Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't