|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1993-3-12
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|
pubmed:abstractText |
Patients with squamous cell carcinoma of the head and neck have a 10-30% risk of developing a second primary tumor. The concept of "field cancerization" assumes that the whole upper aerodigestive tract is affected and prone to malignant transformation. This study was undertaken to investigate the value of a panel of monoclonal antibodies to identify biomarkers in oral mucosa associated with cancer risk. Such biomarkers may be suitable candidates to serve as intermediate endpoints in cancer chemoprevention trials.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0008-543X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
71
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
825-30
|
|
pubmed:dateRevised |
2010-3-24
|
|
pubmed:meshHeading |
pubmed-meshheading:8431864-Adult,
pubmed-meshheading:8431864-Aged,
pubmed-meshheading:8431864-Aged, 80 and over,
pubmed-meshheading:8431864-Antibodies, Monoclonal,
pubmed-meshheading:8431864-Anticarcinogenic Agents,
pubmed-meshheading:8431864-Antigens, Neoplasm,
pubmed-meshheading:8431864-Carcinoma, Squamous Cell,
pubmed-meshheading:8431864-Cell Differentiation,
pubmed-meshheading:8431864-Cell Transformation, Neoplastic,
pubmed-meshheading:8431864-Evaluation Studies as Topic,
pubmed-meshheading:8431864-Female,
pubmed-meshheading:8431864-Humans,
pubmed-meshheading:8431864-Immunohistochemistry,
pubmed-meshheading:8431864-Male,
pubmed-meshheading:8431864-Middle Aged,
pubmed-meshheading:8431864-Mouth Mucosa,
pubmed-meshheading:8431864-Mouth Neoplasms,
pubmed-meshheading:8431864-Neoplasms, Second Primary,
pubmed-meshheading:8431864-Risk Factors,
pubmed-meshheading:8431864-Tumor Markers, Biological
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|
pubmed:year |
1993
|
|
pubmed:articleTitle |
A panel of biomarkers of carcinogenesis of the upper aerodigestive tract as potential intermediate endpoints in chemoprevention trials.
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|
pubmed:affiliation |
Department of Otorhinolaryngology/Head and Neck Surgery, Free University Hospital, Amsterdam, The Netherlands.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
|
