Linked Life Data

8431657

Source:http://linkedlifedata.com/resource/pubmed/id/8431657

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-3-18
pubmed:abstractText
Based on the prevailing interpretation of recent data implicating donor homozygosity for an HLA haplotype shared with a heterozygous recipient, it is our conclusion that the risk of TA-GVHD for a sibling of the blood donor is about half that of a parent or a child, and the risk for a grandparent, a grandchild, or a blood-related aunt, uncle, niece, or nephew is about the same as the risk for the donor's sibling. Consequently, the current recommendation and the practice of irradiating cellular blood products for transfusion to first-degree relatives but not for transfusion to more distant relatives is insufficient. We believe that the recommendation for prophylactic irradiation of cellular blood products, based on the current understanding of its apparent safety, should be extended at least to include transfusion to the donor's grandparents, grandchildren, and blood-related aunts, uncles, nieces, and nephews.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0887-7963
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
37-41
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
HLA homozygosity and the risk of related-donor transfusion-associated graft-versus-host disease.
pubmed:affiliation
Department of Pathology, Oregon Health Sciences University, Portland 97201-3098.
pubmed:publicationType
Journal Article, Review