Linked Life Data

8430147

Source:http://linkedlifedata.com/resource/pubmed/id/8430147

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-3-11
pubmed:abstractText
Several authors have postulated that the standard McFarlane-type dorsal rat flap model can survive as a graft. Therefore, in an effort to better understand the metabolic support governing the survival of this flap, five flap designs on the dorsal surface of the rat were studied. Each was manipulated to control progressively for the metabolic support to the flap by means of skin-graft and/or skin-flap physiology. The flap designs included (1) a standard McFarlane flap (n = 10), (2) a full-thickness "flap" graft (n = 10), (3) a McFarlane flap separated from the bed with plastic sheeting (n = 9), (4) a McFarlane flap separated from the bed by closing the wound beneath the flap (n = 29), and (5) flaps raised as in group 4 after a 2-week delay procedure (n = 9). Based on direct comparisons of both the pattern of necrosis and the surviving surface area in each group, we conclude that (1) the distal aspect of the dorsal rat flap can survive as a graft when in contact with the underlying bed, (2) the "take" of the flap as a graft is variable, and (3) to serve as a reasonable indicator of human flap behavior, the skin-graft effect must be controlled for by separating the flap from the underlying bed.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0032-1052
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-21
pubmed:dateRevised
2011-2-16
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The dorsal skin-flap model in the rat: factors influencing survival.
pubmed:affiliation
Department of Plastic and Reconstructive Surgery, Grand Rapids Area Medical Education Center, Mich.
pubmed:publicationType
Journal Article