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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1977-4-30
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pubmed:abstractText |
The effects of prolonged enflurane and halothane administration on urine-concentrating ability were determined in volunteers by examining their responses to vasopressin before anesthesia and on days 1 and 5 after anesthesia. A significant decrease in maximum urinary osmolality of 264 +/- 34 mOsm/kg (26 per cent of the preanesthetic value) was present on day 1 after enflurane anesthesia, whereas subjects anesthetized with halothane had a significant increase in maximum urinary osmolality of 120 +/- 44 mOsm/kg. Serum inorganic fluoride level peaked at 33.6 muM and remained above 20 muM for approximately 18 hours. Thus, the threshold level for inorganic fluoride nephrotoxicity is lower than previously suspected.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-3022
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
265-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:842883-Adult,
pubmed-meshheading:842883-Bromides,
pubmed-meshheading:842883-Enflurane,
pubmed-meshheading:842883-Fluorides,
pubmed-meshheading:842883-Glomerular Filtration Rate,
pubmed-meshheading:842883-Halothane,
pubmed-meshheading:842883-Humans,
pubmed-meshheading:842883-Kidney Concentrating Ability,
pubmed-meshheading:842883-Male,
pubmed-meshheading:842883-Methyl Ethers,
pubmed-meshheading:842883-Osmolar Concentration,
pubmed-meshheading:842883-Vasopressins
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pubmed:year |
1977
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|
pubmed:articleTitle |
Inorganic fluoride nephrotoxicity: prolonged enflurane and halothane anesthesia in volunteers.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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