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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-3-5
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pubmed:abstractText |
While the association of morphea and systemic sclerosis (SSc) is considered to be a rare condition, we observed well-demarcated sclerotic skin changes indistinguishable from morphea in 9 of 135 SSc patients who visited our clinic during the last decade. We consider this rate of incidence (6.7%) to be high enough to consider morphea to be one of the skin involvements of SSc. There was a significantly (p < 0.01) higher incidence of morphea in males (3 of 5) than in females (6 of 130). Only 3 of 111 SSc patients positive for antinuclear antibody (ANA) also showed morphea, whereas 6 of 9 patients negative for ANA showed morphea (p < 0.01). Although the mechanism underlying the development of morphea in SSc patients remains unknown, our observations suggest a heterogeneous pathogenesis related to SSc gender and ANA type.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1018-8665
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
186
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8428037-Adult,
pubmed-meshheading:8428037-Antibodies, Antinuclear,
pubmed-meshheading:8428037-Collagen,
pubmed-meshheading:8428037-Female,
pubmed-meshheading:8428037-Humans,
pubmed-meshheading:8428037-Male,
pubmed-meshheading:8428037-Middle Aged,
pubmed-meshheading:8428037-Scleroderma, Localized,
pubmed-meshheading:8428037-Scleroderma, Systemic
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pubmed:year |
1993
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pubmed:articleTitle |
Coexistence of morphea and systemic sclerosis.
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pubmed:affiliation |
Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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